Connect with us

Science

With UK nod, Merck drug becomes world’s 1st pill for Covid treatment.

Published

on

Britain on Thursday became the primary country within the world to approve a doubtless game-changing COVID-19 antiviral pill conjointly developed by U.S.-based Merck and Ridgeback Biotherapeutics, in an exceedingly boost to the fight against the pandemic.

Britain’s Medicines and health care products regulatory authority (MHRA) suggested the drug, molnupiravir, be used as before long as attainable following a positive COVID-19 check and among 5 days of the onset of symptoms, citing clinical knowledge.

This is the primary oral antiviral treatment for COVID-19 to induce approved, with the inexperienced lightweight returning before potential U.S. restrictive clearance. U.S. advisers can meet this month to vote on whether or not molnupiravir ought to be licensed.

Advertisement

Treatments to tackle the pandemic, that has killed over 5.2 million individuals worldwide, have thus far centered principally on vaccines. different choices, together with Gilead’s infused antiviral remdesivir and generic steroid corticosteroid, area unit usually solely given when a patient has been hospitalised.

Merck’s Molnupiravir has been closely watched since knowledge last month showed it may fraction the probabilities of dying or being hospitalised for those most in danger of developing severe COVID-19 once given early within the sickness.

The drug, to be branded Lagevrio in United Kingdom of Great Britain and Northern Ireland, is meant to introduce errors into the genetic code of the virus that causes COVID-19 and is taken doubly every day for 5 days.

Advertisement

The British government and also the country’s National Health Service (NHS) can make sure however the treatment are going to be deployed to patients in “due course”.

“We area unit performing at pace across the govt. and with the NHS to line out plans to deploy molnupiravir to patients through a national study as before long as attainable,” health secretary Sajid Javid same in an exceedingly statement.

The speedy approval in United Kingdom of Great Britain and Northern Ireland comes because the government struggles to tame soaring infections.

Advertisement

The country has concerning 40,000 daily cases of COVID-19, in keeping with the newest seven-day average. That total is second solely to the roughly 74,000 every day within the us, that has 5 times a lot of individuals.

Data free on Wed night showed COVID-19 prevalence in European country hit its highest level on record last month, light-emitting diode by a high numbers of cases in youngsters and a surge within the south-west of the country.

Pressure is growing on the govt. to implement its “Plan B” geared toward protective the NHS from unsustainable demands, involving mask mandates, immunogen passes and work-from-home orders.

Advertisement

In a separate statement, Merck same it had been expecting to supply ten million courses of the treatment by the top of this year, with a minimum of twenty million set to be factory-made in 2022.

The U.S. based mostly drugmaker’s shares were up two.1% at $90.54 before the market open.

Pfizer and Roche also are sport to develop easy-to-administer antiviral pills for COVID-19. Pfizer last month began an oversized study of its oral medicine for the interference of COVID-19 in individuals exposed to the coronavirus.

Advertisement

Merck’s molnupiravir is additionally being studied in an exceedingly late-stage trial for preventing infection.

Viral sequencing done thus far has shown molnupiravir is effective against all variants of the coronavirus, Merck has same, together with the more-infectious Delta, that is to blame for the worldwide surge in hospitalizations and deaths recently.

While it’s not nevertheless clear once Merck can deliver doses to United Kingdom of Great Britain and Northern Ireland, the corporate has same it’s committed to providing timely access to its drug globally with plans for bed valuation aligned with a country’s ability to pay.

Advertisement

Merck is additionally in talks with generic drugmakers concerning increasing producing licences to make offer of the treatment.

Science

Have Omicron Symptoms But Test Showed Negative Result? Here’s An Explanation From Doctor

Dr. Harish Chafle states that Omicron symptoms could be divided into three categories, which are: the most prevalent, less common, and severe.

Published

on

omicron symptoms

Do you see or feel Omicron symptoms of Covid 19 in yourself? Also, have you gone through the Corona test, but the result came negative despite having visible signs of the virus infection?  Doctors have admitted the number of people returning with negative RT-PCR test results but have been suffering from the symptoms. Doctors have pointed out several reasons behind negative results while the person has Omicron symptoms.

According to Dr. Bharesh Dedhia, Chief Consultant, Critical Care at P. D. Hinduja Hospital & Medical Research Centre of Khar Unit, inappropriate methods of conducting tests, uncleanliness, and negligence in sample collection and storage are responsible for incorrect test results.

Also Read: Kerala Covid Cases Increasing At Alarming Rate! TPR Raises Close To 50 Percent

Advertisement

“RT-PCR test might return with a negative report for several Omicron variants, specifically the Rapid Antigen Test (RAT) since we notice that the RAT’s precision is roughly 50 percent,” says the researcher “Dr. Bharesh Dedhia, while explaining the scenario.

My conclusion is that the fact that the viral load is relatively minimal. As a result, we have a term known as a CT value, also recognized as a cyclic threshold value. The CT score is deemed negative if it is more than 35, according to the International Commission on Medical Radiology (ICMR). Accordingly, if someone’s viral load is exceptionally modest, their cyclic threshold would be higher than 35, and the covid test would be considered negative. Furthermore, he points out that specific Omicron variants might come back with a negative result in RT-PCR tests.

Also Read: Swiggy Raises Funding In Series K Round, Total Market Value Goes Up To $10.7 Billion

Advertisement

The bulk of RT-PCR tests confirms the presence of newly found variants of Covid. When the S gene drop is located in the RT-PCR test, the Omicron variation is most likely to be present, and when the S gene is found in the test, the Delta variant is most likely to be present. This is how the RT-PCR identifies the occurrence of the new mutation. Gene sequencing should be implemented to corroborate the findings, ” Dr. Dedhia describes in detail. To distinguish between two varieties of the Covid-19  virus, genome sequencing is used. The use of Genome sequencing helps to enhance the efficacy of treatment.

Also Read: New Feature On CoWIN Portal Allows To Add Up To 6 Beneficiaries Per Account, More Features Introduced too

If a patient has standard Covid signs and the RT PCR results are negative, they should isolate themselves for about seven days before getting medical care. The patient may also retest the home test and the RT PCR after the fifth or sixth day to see whether the results have changed and are positive or have remained negative throughout the isolation period.

Advertisement

Centers for Disease Control and Prevention in the United States state the five most prevalent symptoms of the Omicron variant of Covid are cough, tiredness, congestion, runny nose, and widespread body pain.

Senior Consultant In Pulmonology and Critical Care  Dr. Harish Chafle states that Omicron symptoms could be divided into three categories, which are: the most prevalent, less common, and severe.

Also Read: Oppo Reno 7 Lineup Launching Soon On India’s Biggest ECom Site! See Price, Specifications

Advertisement

The Most Prevalent Omicron Symptoms Are As Follows:

Temperature, coughing, fatigue, and a lack of smell or taste.

Less Prevalent Omicron Symptoms

Sore throat, fever, stiffness, headaches, diarrhea, redness on the skin, discoloration of fingers or toes, and red or inflamed eyes 

Severe Omicron Symptoms

Breathing difficulties or breathlessness, the inability of speaking or movement, disorientation, or chest discomfort

Advertisement

Also Read: Indian Tech Giant Tech Mahindra Acquires Com Tec Co IT Ltd For $310 Million, Bolsters Its Presence In Tech Industry

Continue Reading

Science

Kerala Covid Cases Increasing At Alarming Rate! TPR Raises Close To 50 Percent

There has been a significant elevation in the Kerala covid cases during the last few days. As per the available data,  the state has 2,85,365 Covid patients currently undergoing treatment.

Published

on

kerala covid cases

Kerala Covid cases are increasing at an alarming rate. In the past 24 hours, the state has registered 55,475 occurrences of covid, pushing the state’s test positive rate to 49.9 percent, an increase from the previously recorded figure.  The TPR, the first time after several months, has reached close to 50 percent. The newly registered TPR clearly shows that one out of two individuals tested for the Covid-19 was diagnosed positive for the test.

Additionally, 70 related fatalities and 84 deaths were freshly recognized as Covid-19 fatalities as per the changed guidelines, bringing the total number of deaths in the state to 52,141. There has been a significant elevation in the Kerala covid cases during the last few days. As per the available data,  the state has 2,85,365 Covid patients currently undergoing treatment.

Breakdown Of Active Kerala Covid Cases

Kottayam – 3,672,  Kozhikode – 4,432,  Palakkad – 3,550,  Kasaragod – 1,728 Malappuram – 3,138, Idukki – 2,452,, Kannur – 2,578, Kollam – 4,452, Alappuzha – 2,561, Pathanamthitta – 2,311, and Wayanad – 1,070, and Thrissur – 5,520 people.

Advertisement

Also Read: New Feature On CoWIN Portal Allows To Add Up To 6 Beneficiaries Per Account, More Features Introduced too

The Health Department of Kerala said that the covid test centers had collected 1,12,281 covid samples in the 24 hours. Out of them, 55,475 samples tested positive for the virus infection. The report available on the Kerala government’s covid portal also revealed that the test positivity rate has risen over 44 percent.

According to an official media statement of the health department of Kerala, there are 4,42,466 covid patients under supervision across the state, including 10,342 of them being kept in isolation wards at different hospitals. “At this moment, the active count of Kerala covid cases is 2,85,365, with just 3.8 percent of them admitted to hospitals,” according to the press statement. On Tuesday, the state confirmed 154 COVID-19-related fatalities, raising the total number of deaths to 52,141.

Advertisement

Also Read: Oppo Reno 7 Lineup Launching Soon On India’s Biggest ECom Site! See Price, Specifications

Dr. Mansukh Mandaviya, the Union Health Minister, urged state governments and union territories to increase covid testing in places where the active count has declined in recent times. Furthermore, Dr. Mansukh  Mandaviya advised authorities from the union territories and states to share Covid-19 testing and immunization statistics on a regular basis during a meeting with the authorities of these states and union territories A considerable number of patients are choosing for home isolation. So, the health minister instructed the state administration to monitor the infected people according to national rules closely.

Also Read: Reliance JioFibre Broadband Dominates BSNL And Airtel In Home Broadband Segment, Reliance Gained 2.01 Million Users, VIL Lost 0.1

Advertisement

Statistics from the Union Ministry of Health and Family Welfare show that India recorded 2,55,874 Covid-19 patients in the past 24 hours on Tuesday, decreasing the previous day’s total of 3,06,064 cases. The health ministry’s figures reveal that over 614 deaths occurred in the last 24 hours, pushing India’s covid death count to 4,90,462. The daily positivity rate is 15.52 percent, and the weekly positivity rate is 17.17 percent. The good news is that daily, and weekly TPR is lower than the previous count. On the other hand, the count of patients recovered from the covid infection rose to 3,70,71,898.   As many as  2,67,753 infected people recovered from the Covid-19 virus in the previous 24 hours.

Continue Reading

Science

New Feature On CoWIN Portal Allows To Add Up To 6 Beneficiaries Per Account, More Features Introduced too

Users can raise an issue on the CoWIN portal to correct their vaccination status. Due to unintended data entry errors, while filling up vaccination beneficiary status, a few cases showed incorrect vaccination status, said the central government.

Published

on

cowin portal

CoWIN portal will now allow the addition of up to 6 beneficiaries in the registered using one mobile number. The central government of India announced its decision to extend the maximum number of beneficiaries to apply for receiving vaccination doses. Until now, the maximum number of applicants was capped at four per registered account.

Along with enlarging the number of beneficiaries, the central government of India has introduced some additional features on the COWIN portal. Newly added features on the portal will allow the users to change their vaccination status from fully vaccinated to partially vaccinated or not vaccinated and vice versa. Before the rollout of the vaccination status update feature, users could change their name, gender and year of birth on the CoWIN portal. 

Users can raise an issue on the CoWIN portal to correct their vaccination status. Due to unintended data entry errors, while filling up vaccination beneficiary status, a few cases showed incorrect vaccination status, said the central government.

Advertisement

Also Read: Omicron Variant 3 Times More Infectious Than Delta

“Revoking the vaccination status may need three to seven days after posting the online request on the CoWIN portal using the raise an issue facility for the updates to take effect. After the revised vaccination status has been correctly updated in the system, such individuals may get their due vaccine dosage, at their closest vaccination centre, in accordance with the existing standard norms,” the central government added further.

Recently, the central government of India commenced a vaccination drive for below 18 children and administration of booster doses to older people at the same time. Meanwhile, the Union Government of Health and Family Welfare said on Friday that India’s gross Covid-19 vaccination coverage drive had crossed 160.43 crores after the administration of above 70 lakh jabs in the previous 24 hours, according to the ministry.

Advertisement

More than 159.91 crore vaccine shots have been distributed to union territories and states till now, mostly via free vaccination drive of the central government of India and the direct state procurement category of the state administrations. State and territorial governments have been receiving free Covid-19 vaccinations from the central government as part of a countrywide inoculation campaign, which has been supported by the state government as well. 

Also Read: Omicron poses ‘very high’ global risk, the world must be prepared

Procedure To Applying For Modifications On CoWIN Portal

Step 1. Log on to www.cowin.gov.in

Advertisement

Step 2. Sign in to your account with the help of your 10-digit mobile number

Step 3. Type in your 6-digit One Time Password received on your mobile number.

Step 4. Verify the OTP to log into your account.

Advertisement

Step 5. Navigate to your accounts details section

Step 6. If you are fully or partially vaccinated, there will be an option next to your vaccination status to raise an issue over your incorrect vaccination information.

Step 7. The system will ask you about the issue. Click on the error you want to get resolved.

Advertisement

After that, the change request goes under review, which might get accepted between three to seven days. Once the mistakes are rectified, the users will be able to get an errorless vaccination certificate.

Also Read: Israeli Startup Develops Balloons To Capture Carbon

Advertisement
Continue Reading

Trending

%d bloggers like this: